Dental caries is an irreversible microbial disease of the calcified tissues of the teeth which is characterized by demineralization of the inorganic portion and destruction of the organic substance of the tooth which often leads to cavitation dental caries is a multifactorial disease which is caused by host agent and environmental factors. Streptococcus mutans play a key role for the development of dental caries and that a vaccine directed against this microorganism could be a valuable adjunct to existing preventive measures in some . Dental caries hence the prevention and control of dental caries is the main aim of public health eventually the ultimate objective of public health is the elimination of the disease itself recently dental caries vaccines have been developed for the prevention of dental caries these dental caries vaccines are still in the early stages. O the main target population for a caries vaccine would be young children infants o safety issues are more stringent in children o most adults have already experienced dental caries therefore may not see good responses o senescence of some of the mucosal immune tissues in adults eg tonsils which may be active in children
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